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  Indian J Med Microbiol
 

Figure 7: (a) Light micrograph of the control retina. After 1 week: (b) Diabetic retinopathy (DR) showed severe edema in the cytoplasm of retinal pigmented epithelium (RPE) (red arrow) and swelling in the retinal ganglion cells (RGCs), (c) DR group exposed to low level laser therapy (DR + LLLT) showed edema in the RPE (black arrow), fragmentation in the inner nuclear layer (red arrows), swelling in the RGCs. Two weeks: (d) DR showed congestion of the retinal capillaries in the nerve fiber layer (NFL), thickening of the lining endothelial cells capillaries (black arrow) and swelling of the RGCs (red arrow), (e) DR + LLLT showed swelling in RGCs and the capillaries of NFL (red arrow). Four weeks: (f) DR showed edema and disorganization in the photoreceptors layer (PRL), swelling of RGCs, (g): DR + LLLT showed normal retina. Six weeks: (h) DR showed edema of the outer segment of PRL (red arrow), outer plexiform layer (black arrow), with thick-wall capillary (red arrow) and scanty cytoplasm of RGCs (i) DR + LLLT showed normal retina. (Toluidine blue, scale bar: 20 μm)

Figure 7: (a) Light micrograph of the control retina. After 1 week: (b) Diabetic retinopathy (DR) showed severe edema in the cytoplasm of retinal pigmented epithelium (RPE) (red arrow) and swelling in the retinal ganglion cells (RGCs), (c) DR group exposed to low level laser therapy (DR + LLLT) showed edema in the RPE (black arrow), fragmentation in the inner nuclear layer (red arrows), swelling in the RGCs. Two weeks: (d) DR showed congestion of the retinal capillaries in the nerve fiber layer (NFL), thickening of the lining endothelial cells capillaries (black arrow) and swelling of the RGCs (red arrow), (e) DR + LLLT showed swelling in RGCs and the capillaries of NFL (red arrow). Four weeks: (f) DR showed edema and disorganization in the photoreceptors layer (PRL), swelling of RGCs, (g): DR + LLLT showed normal retina. Six weeks: (h) DR showed edema of the outer segment of PRL (red arrow), outer plexiform layer (black arrow), with thick-wall capillary (red arrow) and scanty cytoplasm of RGCs (i) DR + LLLT showed normal retina. (Toluidine blue, scale bar: 20 μm)